All Relations between sn and Substantia nigra

Publication Sentence Publish Date Extraction Date Species
Mika Shimoji, Fernando Pagan, Edward B Healton, Italo Mocchett. CXCR4 and CXCL12 expression is increased in the nigro-striatal system of Parkinson's disease. Neurotoxicity research. vol 16. issue 3. 2010-01-25. PMID:19551455. in the human substantia nigra (sn), cxcr4 immunoreactivity was high in dopaminergic neurons. 2010-01-25 2023-08-12 mouse
Julie A Moreno, Elizabeth C Yeomans, Karin M Streifel, Bryan L Brattin, Robert J Taylor, Ronald B Tjalken. Age-dependent susceptibility to manganese-induced neurological dysfunction. Toxicological sciences : an official journal of the Society of Toxicology. vol 112. issue 2. 2010-01-25. PMID:19812362. levels of mn, fe, and cu were determined by inductively coupled plasma-mass spectrometry, with the greatest accumulation of mn detected in juvenile mice in the striatum, substantia nigra (sn), and cortex. 2010-01-25 2023-08-12 mouse
Noémie Bérubé-Carrière, Mustapha Riad, Grégory Dal Bo, Daniel Lévesque, Louis-Eric Trudeau, Laurent Descarrie. The dual dopamine-glutamate phenotype of growing mesencephalic neurons regresses in mature rat brain. The Journal of comparative neurology. vol 517. issue 6. 2010-01-25. PMID:19844994. very few neurons expressed both mrnas in the vta and substantia nigra (sn) of p90 rats, even after neonatal 6-ohda. 2010-01-25 2023-08-12 rat
Ilva Putzier, Paul H M Kullmann, John P Horn, Edwin S Levita. Cav1.3 channel voltage dependence, not Ca2+ selectivity, drives pacemaker activity and amplifies bursts in nigral dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 49. 2010-01-19. PMID:20007466. ca(v)1.3 (alpha 1d) l-type ca(2+) channels have been implicated in substantia nigra (sn) dopamine (da) neuron pacemaking and vulnerability to parkinson's disease. 2010-01-19 2023-08-12 rat
Sarah N Blythe, David Wokosin, Jeremy F Atherton, Mark D Beva. Cellular mechanisms underlying burst firing in substantia nigra dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 49. 2010-01-19. PMID:20007477. burst firing of substantia nigra dopamine (sn da) neurons is believed to represent an important teaching signal that instructs synaptic plasticity and associative learning. 2010-01-19 2023-08-12 Not clear
David Weise, Reinhard Lorenz, Mira Schliesser, Andreas Schirbel, Karlheinz Reiners, Joseph Classe. Substantia nigra echogenicity: A structural correlate of functional impairment of the dopaminergic striatal projection in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. vol 24. issue 11. 2010-01-15. PMID:19514075. transcranial sonography (tcs) reveals abnormal spatial extension of substantia nigra (sn) echogenicity in a high proportion of patients with parkinson's disease (pd). 2010-01-15 2023-08-12 Not clear
Víctor Tapias, Germaine Escames, Luis C López, Ana López, Encarnación Camacho, María D Carrión, Antonio Entrena, Miguel A Gallo, Antonio Espinosa, Darío Acuña-Castroviej. Melatonin and its brain metabolite N(1)-acetyl-5-methoxykynuramine prevent mitochondrial nitric oxide synthase induction in parkinsonian mice. Journal of neuroscience research. vol 87. issue 13. 2010-01-12. PMID:19437546. mitochondria from substantia nigra (sn) and, to a lesser extent, from striatum (st) showed a significant increase in i-mtnos activity, nitrite levels, oxidative stress, and complex i inhibition after mptp treatment. 2010-01-12 2023-08-12 mouse
Jun Jia, ZuoLi Sun, Bo Li, YanLi Pan, HaoMin Wang, Xuan Wang, Fen Yu, LiMin Liu, LiJuan Zhang, XiaoMin Wan. Electro-acupuncture stimulation improves motor disorders in Parkinsonian rats. Behavioural brain research. vol 205. issue 1. 2010-01-12. PMID:19549545. tyrosine hydroxylase immunohistochemical staining revealed that ea at 100 hz protected axotomized dopaminergic neurons from degeneration in the substantia nigra (sn). 2010-01-12 2023-08-12 rat
Louisa C Johnston, Jamie Eberling, Philip Pivirotto, Piotr Hadaczek, Howard J Federoff, John Forsayeth, Krystof S Bankiewic. Clinically relevant effects of convection-enhanced delivery of AAV2-GDNF on the dopaminergic nigrostriatal pathway in aged rhesus monkeys. Human gene therapy. vol 20. issue 5. 2010-01-11. PMID:19203243. monkeys that had received putaminal phosphate-buffered saline (pbs) infusions additionally received either pbs or hd aav2-gdnf in the right substantia nigra (sn). 2010-01-11 2023-08-12 human
Deepinder Kaur, Subramanian Rajagopalan, Julie K Anderse. Chronic expression of H-ferritin in dopaminergic midbrain neurons results in an age-related expansion of the labile iron pool and subsequent neurodegeneration: implications for Parkinson's disease. Brain research. vol 1297. 2010-01-08. PMID:19699718. while ferritin elevation within dopaminergic (da) neurons of the substantia nigra (sn) is protective against neurodegeneration elicited by two toxin models of parkinson's disease (pd), mptp and paraquat, in young animals, its prolonged elevation results in a selective age-related neurodegeneration. 2010-01-08 2023-08-12 mouse
Patricia A Lawlor, Ross J Bland, Alexandre Mouravlev, Deborah Young, Matthew J Durin. Efficient gene delivery and selective transduction of glial cells in the mammalian brain by AAV serotypes isolated from nonhuman primates. Molecular therapy : the journal of the American Society of Gene Therapy. vol 17. issue 10. 2010-01-05. PMID:19638961. titer-matched vectors encoding the enhanced green fluorescent protein (egfp) reporter, driven by the constitutive cag promoter, were injected into the hippocampus, striatum, or substantia nigra (sn) of adult rats. 2010-01-05 2023-08-12 rat
Deepinder Kaur, Donna Lee, Subramanian Ragapolan, Julie K Anderse. Glutathione depletion in immortalized midbrain-derived dopaminergic neurons results in increases in the labile iron pool: implications for Parkinson's disease. Free radical biology & medicine. vol 46. issue 5. 2009-12-15. PMID:19118623. glutathione depletion is one of the earliest detectable events in the parkinsonian substantia nigra (sn), but whether it is causative for ensuing molecular events associated with the disease is unknown. 2009-12-15 2023-08-12 Not clear
J Scheel-Krüger, J Arnt, G Magelun. Behavioural stimulation induced by muscimol and other GABA agonists injected into the substantia nigra. Neuroscience letters. vol 4. issue 6. 2009-12-15. PMID:19556189. the unilateral injection of putative gaba agonists, muscimol, baclofen, imidazole acetic acid and gaba into the caudal area of substantia nigra (sn, zona reticulata) induced immediately a contralateral turning, whereas the antogonists picrotoxin and bicuculline methiodide induced ipsilateral turning. 2009-12-15 2023-08-12 rat
J M Deniau, C Hammond, G Chevalier, J Fege. Evidence for branched subthalamic nucleus projections to substantia nigra, entopeduncular nucleus and globus pallidus. Neuroscience letters. vol 9. issue 2-3. 2009-12-15. PMID:19605204. the organization of subthalamic (stn) projections to the substantia nigra (sn), entopeduncular nucleus (en) and globus pallidus (gp) were studied in the rat. 2009-12-15 2023-08-12 rat
Andrea Tarozzi, Fabiana Morroni, Adriana Merlicco, Silvana Hrelia, Cristina Angeloni, Giorgio Cantelli-Forti, Patrizia Hreli. Sulforaphane as an inducer of glutathione prevents oxidative stress-induced cell death in a dopaminergic-like neuroblastoma cell line. Journal of neurochemistry. vol 111. issue 5. 2009-12-11. PMID:19780897. the total gsh depletion observed in the substantia nigra (sn) appears to be responsible for subsequent oxidative stress (os), mitochondrial dysfunction, and dopaminergic cell loss in patients with parkinson's disease. 2009-12-11 2023-08-12 Not clear
Mariana Astiz, María J T de Alaniz, Carlos Alberto Marr. Effect of pesticides on cell survival in liver and brain rat tissues. Ecotoxicology and environmental safety. vol 72. issue 7. 2009-12-07. PMID:19493570. 1/250 ld50, three times a week for 5 weeks) caused loss of mitochondrial transmembrane potential and cardiolipin content, especially in substantia nigra (sn), with a concomitant increase of fatty acid peroxidation. 2009-12-07 2023-08-12 human
Marta Biagioli, Milena Pinto, Daniela Cesselli, Marta Zaninello, Dejan Lazarevic, Paola Roncaglia, Roberto Simone, Christina Vlachouli, Charles Plessy, Nicolas Bertin, Antonio Beltrami, Kazuto Kobayashi, Vittorio Gallo, Claudio Santoro, Isidro Ferrer, Stefano Rivella, Carlo Alberto Beltrami, Piero Carninci, Elio Raviola, Stefano Gustincic. Unexpected expression of alpha- and beta-globin in mesencephalic dopaminergic neurons and glial cells. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 36. 2009-12-07. PMID:19717439. the mesencephalic dopaminergic (mda) cell system is composed of two major groups of projecting cells in the substantia nigra (sn) (a9 neurons) and the ventral tegmental area (vta) (a10 cells). 2009-12-07 2023-08-12 mouse
Ingrid Moráles, Angel Fuentes, Tomas Gonzalez-Hernandez, Manuel Rodrígue. Osmosensitive response of glutamate in the substantia nigra. Experimental neurology. vol 220. issue 2. 2009-12-07. PMID:19766632. previous studies have suggested the increase of extracellular glutamate (glu) in the substantia nigra (sn) as a cause of dopamine-cell degeneration (excitotoxicity) in parkinson's disease (pd). 2009-12-07 2023-08-12 rat
Roy A Wis. Roles for nigrostriatal--not just mesocorticolimbic--dopamine in reward and addiction. Trends in neurosciences. vol 32. issue 10. 2009-12-03. PMID:19758714. forebrain dopamine circuitry has traditionally been studied by two largely independent specialist groups: students of parkinson's disease who study the nigrostriatal dopamine system that originates in the substantia nigra (sn), and students of motivation and addiction who study the role of the mesolimbic and mesocortical dopamine systems that originate in the ventral tegmental area (vta). 2009-12-03 2023-08-12 Not clear
K J Schweitzer, S Behnke, I Liepelt, B Wolf, C Grosser, J Godau, A Gaenslen, T Bruessel, A Wendt, F Abel, A Müller, T Gasser, D Ber. Cross-sectional study discloses a positive family history for Parkinson's disease and male gender as epidemiological risk factors for substantia nigra hyperechogenicity. Journal of neural transmission (Vienna, Austria : 1996). vol 114. issue 9. 2009-11-27. PMID:17446999. hyperechogenicity of the substantia nigra (sn) has been proposed to be a typical finding in parkinson's disease (pd) and a marker of vulnerability to nigrostriatal dysfunction in healthy subjects. 2009-11-27 2023-08-12 human