| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Denis Pavă. A Dopamine Hypothesis of Autism Spectrum Disorder. Developmental neuroscience. vol 39. issue 5. 2018-05-22. PMID:28750400. |
in this paper, we present such a hypothesis by proposing that autistic behavior arises from dysfunctions in the midbrain dopaminergic system. |
2018-05-22 |
2023-08-13 |
human |
| Nicole Gennet, Claudia Tamburini, Xinsheng Nan, Meng L. FolR1: a novel cell surface marker for isolating midbrain dopamine neural progenitors and nascent dopamine neurons. Scientific reports. vol 6. 2018-05-16. PMID:27580818. |
midbrain dopaminergic neurons (mesda) are the nerve cells preferentially lost in the brains of parkinson's disease patients. |
2018-05-16 |
2023-08-13 |
mouse |
| Mi Wang, Wael Saasouh, Thomas Botsford, Allen Keebler, Andrew Zura, Michael S Benninger, Rafi Avitsia. Postoperative Stridor and Acute Respiratory Failure After Parkinson Disease Deep Brain Stimulator Placement: Case Report and Review of Literature. World neurosurgery. vol 111. 2018-05-15. PMID:29229347. |
parkinson disease (pd), a neurodegenerative disorder characterized by loss of dopaminergic neurons in the substantia nigra of the midbrain, is commonly thought of as a motion disorder, but it can have significant effect on the respiratory system. |
2018-05-15 |
2023-08-13 |
Not clear |
| Arjun Ramakrishnan, Yoon Woo Byun, Kyle Rand, Christian E Pedersen, Mikhail A Lebedev, Miguel A L Nicoleli. Cortical neurons multiplex reward-related signals along with sensory and motor information. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 24. 2018-05-14. PMID:28559307. |
this influence can be exerted directly upon the primary motor (m1) and somatosensory (s1) cortical areas via the projections from reward-sensitive dopaminergic neurons of the midbrain ventral tegmental areas. |
2018-05-14 |
2023-08-13 |
monkey |
| Rachel A Cliburn, Amy R Dunn, Kristen A Stout, Carlie A Hoffman, Kelly M Lohr, Alison I Bernstein, Emily J Winokur, James Burkett, Yvonne Schmitz, William M Caudle, Gary W Mille. Immunochemical localization of vesicular monoamine transporter 2 (VMAT2) in mouse brain. Journal of chemical neuroanatomy. vol 83-84. 2018-05-11. PMID:27836486. |
we show the distribution of vmat2 in monoaminergic brain regions of mouse brain, notably the midbrain, striatum, olfactory tubercle, dopaminergic paraventricular nuclei, tuberomammillary nucleus, raphe nucleus, and locus coeruleus. |
2018-05-11 |
2023-08-13 |
mouse |
| Panojot Bifsha, Aurelio Balsalobre, Jacques Droui. Specificity of Pitx3-Dependent Gene Regulatory Networks in Subsets of Midbrain Dopamine Neurons. Molecular neurobiology. vol 54. issue 7. 2018-05-10. PMID:27514757. |
dysfunction of midbrain dopaminergic (mda) neurons is involved in parkinson's disease (pd) and neuropsychiatric disorders. |
2018-05-10 |
2023-08-13 |
human |
| Zuzanna Kurowska, Michael Jewett, Per Ludvik Brattås, Itzia Jimenez-Ferrer, Xuyian Kenéz, Tomas Björklund, Ulrika Nordström, Patrik Brundin, Maria Swanber. Identification of Multiple QTLs Linked to Neuropathology in the Engrailed-1 Heterozygous Mouse Model of Parkinson's Disease. Scientific reports. vol 6. 2018-05-09. PMID:27550741. |
motor symptoms in parkinson's disease are attributed to degeneration of midbrain dopaminergic neurons (dns). |
2018-05-09 |
2023-08-13 |
mouse |
| Dan P Covey, Yolanda Mateo, David Sulzer, Joseph F Cheer, David M Lovinge. Endocannabinoid modulation of dopamine neurotransmission. Neuropharmacology. vol 124. 2018-05-09. PMID:28450060. |
the dopaminergic midbrain innervates numerous brain regions where extracellular da release and receptor binding promote short- and long-term changes in postsynaptic neuron function. |
2018-05-09 |
2023-08-13 |
Not clear |
| Ammar Natalwala, Tilo Kunat. Preparation, characterization, and banking of clinical-grade cells for neural transplantation: Scale up, fingerprinting, and genomic stability of stem cell lines. Progress in brain research. vol 230. 2018-05-01. PMID:28552226. |
parkinson's disease is a complex and progressive neurodegenerative condition that is characterized by the severe loss of midbrain dopaminergic (mda) neurons, which innervate the striatum. |
2018-05-01 |
2023-08-13 |
human |
| Agnete Kirkeby, Malin Parmar, Roger A Barke. Strategies for bringing stem cell-derived dopamine neurons to the clinic: A European approach (STEM-PD). Progress in brain research. vol 230. 2018-05-01. PMID:28552228. |
transplantation of human fetal ventral midbrain tissue to the striatum of pd patients has provided proof-of-principle that such an approach can provide long-term clinical benefits with a reduced dependency on any oral dopaminergic agents. |
2018-05-01 |
2023-08-13 |
human |
| Agnete Kirkeby, Malin Parmar, Roger A Barke. Strategies for bringing stem cell-derived dopamine neurons to the clinic: A European approach (STEM-PD). Progress in brain research. vol 230. 2018-05-01. PMID:28552228. |
as a result, alternative cell sources have been explored and the methods for producing authentic midbrain dopaminergic neurons from pluripotent cells have now advanced to a stage which makes it possible to efficiently and reproducibly produce da progenitors at a much higher purity than can be obtained from human fetal tissue. |
2018-05-01 |
2023-08-13 |
human |
| Scott C Vermilyea, Scott Guthrie, Michael Meyer, Kim Smuga-Otto, Katarina Braun, Sara Howden, James A Thomson, Su-Chun Zhang, Marina E Emborg, Thaddeus G Golo. Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Adult Common Marmoset Fibroblasts. Stem cells and development. vol 26. issue 17. 2018-04-30. PMID:28635509. |
exposure to chir99021 and sonic hedgehog (shh) for 12 and 16 days, respectively, patterned the cells toward a ventralized midbrain dopaminergic phenotype, confirmed by expression of foxa2, otx2, en-1, and tyrosine hydroxylase. |
2018-04-30 |
2023-08-13 |
mouse |
| Agnete Prydz, Katja Stahl, Maja Puchades, Nina Davarpaneh, Maria Nadeem, Ole Petter Ottersen, Vidar Gundersen, Mahmood Amiry-Moghadda. Subcellular expression of aquaporin-4 in substantia nigra of normal and MPTP-treated mice. Neuroscience. vol 359. 2018-04-30. PMID:28735099. |
a recent study suggests that the differential susceptibility of midbrain dopaminergic neurons to the parkinsonogenic toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) depends on the expression of aqp4. |
2018-04-30 |
2023-08-13 |
mouse |
| Anne-Laure Bulteau, Natalia P Mena, Françoise Auchère, Irene Lee, Annick Prigent, Christian S Lobsiger, Jean-Michel Camadro, Etienne C Hirsc. Dysfunction of mitochondrial Lon protease and identification of oxidized protein in mouse brain following exposure to MPTP: Implications for Parkinson disease. Free radical biology & medicine. vol 108. 2018-04-26. PMID:28365360. |
using the pd animal model of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (mptp) intoxication in mice, we showed that lon protease expression increased in the ventral mesencephalon of intoxicated animals, concomitantly with the appearance of oxidized proteins and dopaminergic cell loss. |
2018-04-26 |
2023-08-13 |
mouse |
| Tetsuhiro Kikuchi, Asuka Morizane, Daisuke Doi, Keisuke Okita, Masato Nakagawa, Hodaka Yamakado, Haruhisa Inoue, Ryosuke Takahashi, Jun Takahash. Idiopathic Parkinson's disease patient-derived induced pluripotent stem cells function as midbrain dopaminergic neurons in rodent brains. Journal of neuroscience research. vol 95. issue 9. 2018-04-17. PMID:28233934. |
idiopathic parkinson's disease patient-derived induced pluripotent stem cells function as midbrain dopaminergic neurons in rodent brains. |
2018-04-17 |
2023-08-13 |
mouse |
| Thomas Viereckel, Sylvie Dumas, Casey J A Smith-Anttila, Bianca Vlcek, Zisis Bimpisidis, Malin C Lagerström, Åsa Konradsson-Geuken, Åsa Wallén-Mackenzi. Midbrain Gene Screening Identifies a New Mesoaccumbal Glutamatergic Pathway and a Marker for Dopamine Cells Neuroprotected in Parkinson's Disease. Scientific reports. vol 6. 2018-04-16. PMID:27762319. |
here, several unique gene expression patterns were identified in the mouse midbrain of which neurod6 and grp were expressed within different dopaminergic subpopulations of the vta, and trpv1 within a small heterogeneous population. |
2018-04-16 |
2023-08-13 |
mouse |
| Xingzhi Guo, Tingting Liu, Diandian Zhao, Xiaofeng Wang, Dongmei Liu, Yang He, Chang Shan, Yingying Kong, Weiwei Hu, Bei Tao, Lihao Sun, Hongyan Zhao, Shengtian Li, Jianmin Li. FGF18 protects against 6-hydroxydopamine-induced nigrostriatal damage in a rat model of Parkinson's disease. Neuroscience. vol 356. 2018-04-12. PMID:28504195. |
since fibroblast growth factor 18 (fgf18) is involved in midbrain development and has been reported to protect neurons from ischemic injury, we investigated whether fgf18 exerted a protective effect on dopaminergic neurons in the sn. |
2018-04-12 |
2023-08-13 |
rat |
| Dora Reglodi, Justine Renaud, Andrea Tamas, Yousef Tizabi, Sergio B Socías, Elaine Del-Bel, Rita Raisman-Vozar. Novel tactics for neuroprotection in Parkinson's disease: Role of antibiotics, polyphenols and neuropeptides. Progress in neurobiology. vol 155. 2018-04-11. PMID:26542398. |
parkinson's disease is a progressive neurodegenerative disorder characterized by the degeneration of midbrain nigral dopaminergic neurons. |
2018-04-11 |
2023-08-13 |
Not clear |
| Chai K Lim, Francisco J Fernández-Gomez, Nady Braidy, Cristina Estrada, Cristina Costa, Silvia Costa, Alban Bessede, Emiliano Fernandez-Villalba, Anna Zinger, Maria Trinidad Herrero, Gilles J Guillemi. Involvement of the kynurenine pathway in the pathogenesis of Parkinson's disease. Progress in neurobiology. vol 155. 2018-04-11. PMID:27072742. |
parkinson's disease (pd) is a common neurodegenerative disorder characterized by loss of dopaminergic neurons and localized neuroinflammation occurring in the midbrain several years before the actual onset of symptoms. |
2018-04-11 |
2023-08-13 |
Not clear |
| Mahboubeh Ahmadi, Jean-Philippe Dufour, Erich Seifritz, Javad Mirnajafi-Zadeh, Bechara J Saa. The PTZ kindling mouse model of epilepsy exhibits exploratory drive deficits and aberrant activity amongst VTA dopamine neurons in both familiar and novel space. Behavioural brain research. vol 330. 2018-04-09. PMID:28506618. |
we therefore used the pentylenetetrazol (ptz) kindling model of epilepsy in mice to examine potential seizure-associated neuropathologies, focusing on motivation, memory and novel-environment-induced activation of midbrain dopaminergic neurons. |
2018-04-09 |
2023-08-13 |
mouse |