| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E S Savchenko, I B Pevzner, L D Zorova, D N Silachev, V A Babenko, V N Manskikh, M V Gulyaev, Yu A Pirogov, E Yu Plotnikov, D B Zoro. CHANGES IN THE NUMBER OF NEURONS, ASTROCYTES AND MICROGLIA IN THE BRAIN AFTER ISCHEMIC STROKE ASSESSED BY IMMUNOHISTOCHEMISTRY AND IMMUNOBLOTTING. Tsitologiia. vol 58. issue 7. 2018-09-24. PMID:30198664. |
it is known that the mechanisms of damage in the brain after stroke are regulated by combination of severaltypes of cells, primarily of neurons, astrocytes, endothelium and microglia. |
2018-09-24 |
2023-08-13 |
Not clear |
| Rui Liu, Junjian Diao, Shucheng He, Binbin Li, Yuxiang Fei, Yunman Li, Weirong Fan. XQ-1H protects against ischemic stroke by regulating microglia polarization through PPARγ pathway in mice. International immunopharmacology. vol 57. 2018-09-10. PMID:29475098. |
in conclusion, the present study demonstrates that xq-1h alleviated ischemic stroke by regulating balance of pro-/anti-inflammatory microglia polarization through pparγ pathway both in vivo and in vitro, offering an alternative medication for stroke associated with inflammation. |
2018-09-10 |
2023-08-13 |
mouse |
| Yunjie Wang, Yun Huang, Yazhou Xu, Wenchen Ruan, Haojie Wang, Yihua Zhang, Juan M Saavedra, Luyong Zhang, Zhangjian Huang, Tao Pan. A Dual AMPK/Nrf2 Activator Reduces Brain Inflammation After Stroke by Enhancing Microglia M2 Polarization. Antioxidants & redox signaling. vol 28. issue 2. 2018-07-27. PMID:28747068. |
a dual ampk/nrf2 activator reduces brain inflammation after stroke by enhancing microglia m2 polarization. |
2018-07-27 |
2023-08-13 |
Not clear |
| Yunjie Wang, Wenchen Ruan, Junru Mi, Jingzi Xu, Haojie Wang, Zhengyu Cao, Juan M Saavedra, Luyong Zhang, Hansen Lin, Tao Pan. Balasubramide derivative 3C modulates microglia activation via CaMKKβ-dependent AMPK/PGC-1α pathway in neuroinflammatory conditions. Brain, behavior, and immunity. vol 67. 2018-07-11. PMID:28803158. |
promoting the anti-inflammatory activation of microglia might be an effective treatment of stroke. |
2018-07-11 |
2023-08-13 |
mouse |
| K A Jones, S Maltby, M W Plank, M Kluge, M Nilsson, P S Foster, F R Walke. Peripheral immune cells infiltrate into sites of secondary neurodegeneration after ischemic stroke. Brain, behavior, and immunity. vol 67. 2018-07-11. PMID:28911981. |
experimental stroke leads to microglia activation and progressive neuronal loss at sites of secondary neurodegeneration (snd). |
2018-07-11 |
2023-08-13 |
Not clear |
| Radhika Patnala, Thiruma V Arumugam, Neelima Gupta, S Thameem Dhee. HDAC Inhibitor Sodium Butyrate-Mediated Epigenetic Regulation Enhances Neuroprotective Function of Microglia During Ischemic Stroke. Molecular neurobiology. vol 54. issue 8. 2018-07-09. PMID:27722928. |
cerebral ischemia leads to neuroinflammation and activation of microglia which further contribute to stroke pathology. |
2018-07-09 |
2023-08-13 |
mouse |
| Roland G W Staal, Jonathan R Weinstein, Megan Nattini, Manuel Cajina, Gamini Chandresana, Thomas Mölle. Senicapoc: Repurposing a Drug to Target Microglia K Neurochemical research. vol 42. issue 9. 2018-07-09. PMID:28364331. |
senicapoc: repurposing a drug to target microglia k stroke is the leading cause of serious long-term disability and the fifth leading cause of death in the united states. |
2018-07-09 |
2023-08-13 |
Not clear |
| Roland G W Staal, Jonathan R Weinstein, Megan Nattini, Manuel Cajina, Gamini Chandresana, Thomas Mölle. Senicapoc: Repurposing a Drug to Target Microglia K Neurochemical research. vol 42. issue 9. 2018-07-09. PMID:28364331. |
neuroinflammation mediated by microglia and infiltrating peripheral immune cells is a major component of stroke pathophysiology. |
2018-07-09 |
2023-08-13 |
Not clear |
| Jenni E Anttila, Keith W Whitaker, Emily S Wires, Brandon K Harvey, Mikko Airavaar. Role of microglia in ischemic focal stroke and recovery: focus on Toll-like receptors. Progress in neuro-psychopharmacology & biological psychiatry. vol 79. issue Pt A. 2018-07-06. PMID:27389423. |
role of microglia in ischemic focal stroke and recovery: focus on toll-like receptors. |
2018-07-06 |
2023-08-13 |
Not clear |
| Jenni E Anttila, Keith W Whitaker, Emily S Wires, Brandon K Harvey, Mikko Airavaar. Role of microglia in ischemic focal stroke and recovery: focus on Toll-like receptors. Progress in neuro-psychopharmacology & biological psychiatry. vol 79. issue Pt A. 2018-07-06. PMID:27389423. |
this division encompasses the spatial and temporal dynamics of microglia as they participate in the pathophysiological changes that contribute to the symptoms and sequela of a stroke. |
2018-07-06 |
2023-08-13 |
Not clear |
| Jenni E Anttila, Keith W Whitaker, Emily S Wires, Brandon K Harvey, Mikko Airavaar. Role of microglia in ischemic focal stroke and recovery: focus on Toll-like receptors. Progress in neuro-psychopharmacology & biological psychiatry. vol 79. issue Pt A. 2018-07-06. PMID:27389423. |
increasing evidence shows that microglia have a complex role in stroke pathophysiology, and they mediate both detrimental and beneficial effects on stroke outcome. |
2018-07-06 |
2023-08-13 |
Not clear |
| Claudia Espinosa-Garcia, Iqbal Sayeed, Seema Yousuf, Fahim Atif, Elena G Sergeeva, Gretchen N Neigh, Donald G Stei. Stress primes microglial polarization after global ischemia: Therapeutic potential of progesterone. Brain, behavior, and immunity. vol 66. 2018-06-06. PMID:28648389. |
preclinical research suggests that stress primes microglia, resulting in an enhanced reactivity to a subsequent insult and potentially increasing vulnerability to stroke. |
2018-06-06 |
2023-08-13 |
rat |
| Murielle G Kluge, Laura Kracht, Mahmoud Abdolhoseini, Lin Kooi Ong, Sarah J Johnson, Michael Nilsson, Frederick R Walke. Impaired microglia process dynamics post-stroke are specific to sites of secondary neurodegeneration. Glia. vol 65. issue 12. 2018-06-05. PMID:28836304. |
in this study, we used acute slice based multiphoton imaging, to investigate microglia dynamic process movement in mice 14 days after a photothrombotic stroke. |
2018-06-05 |
2023-08-13 |
mouse |
| Masato Kanazawa, Itaru Ninomiya, Masahiro Hatakeyama, Tetsuya Takahashi, Takayoshi Shimohat. Microglia and Monocytes/Macrophages Polarization Reveal Novel Therapeutic Mechanism against Stroke. International journal of molecular sciences. vol 18. issue 10. 2018-05-30. PMID:29027964. |
microglia and monocytes/macrophages polarization reveal novel therapeutic mechanism against stroke. |
2018-05-30 |
2023-08-13 |
Not clear |
| Masato Kanazawa, Itaru Ninomiya, Masahiro Hatakeyama, Tetsuya Takahashi, Takayoshi Shimohat. Microglia and Monocytes/Macrophages Polarization Reveal Novel Therapeutic Mechanism against Stroke. International journal of molecular sciences. vol 18. issue 10. 2018-05-30. PMID:29027964. |
cell-based therapies, using microglia and monocytes/macrophages preconditioned by optimal stimuli and/or any therapies targeting these cells, might be an ideal therapeutic strategy for managing stroke. |
2018-05-30 |
2023-08-13 |
Not clear |
| Masato Kanazawa, Itaru Ninomiya, Masahiro Hatakeyama, Tetsuya Takahashi, Takayoshi Shimohat. Microglia and Monocytes/Macrophages Polarization Reveal Novel Therapeutic Mechanism against Stroke. International journal of molecular sciences. vol 18. issue 10. 2018-05-30. PMID:29027964. |
cell-based therapies using m2-like microglia and monocytes/macrophages might be protective therapeutic strategies against stroke for three reasons. |
2018-05-30 |
2023-08-13 |
Not clear |
| Masato Kanazawa, Itaru Ninomiya, Masahiro Hatakeyama, Tetsuya Takahashi, Takayoshi Shimohat. Microglia and Monocytes/Macrophages Polarization Reveal Novel Therapeutic Mechanism against Stroke. International journal of molecular sciences. vol 18. issue 10. 2018-05-30. PMID:29027964. |
although future translational studies are required, m2-like microglia and monocytes/macrophages therapies are attractive for managing stroke based on their protective functions. |
2018-05-30 |
2023-08-13 |
Not clear |
| Jan-Kolja Strecker, Antje Schmidt, Wolf-Rüdiger Schäbitz, Jens Minneru. Neutrophil granulocytes in cerebral ischemia - Evolution from killers to key players. Neurochemistry international. vol 107. 2018-04-03. PMID:27884770. |
we further report of new findings regarding the interaction of pmns with resident microglia, immigrating macrophages and t cells after stroke. |
2018-04-03 |
2023-08-13 |
Not clear |
| Jin Hwan Lee, Zheng Z Wei, Wenyuan Cao, Soonmi Won, Xiaohuan Gu, Megan Winter, Thomas A Dix, Ling Wei, Shan Ping Y. Regulation of therapeutic hypothermia on inflammatory cytokines, microglia polarization, migration and functional recovery after ischemic stroke in mice. Neurobiology of disease. vol 96. 2018-02-09. PMID:27659107. |
seven days after focal cortical ischemia, microglia activation in the penumbra reached a peak level, which was significantly attenuated by th treatments commenced 30min after stroke. |
2018-02-09 |
2023-08-13 |
mouse |
| Jianguo Xu, Handong Wang, Seok Joon Won, Jayinee Basu, David Kapfhamer, Raymond A Swanso. Microglial activation induced by the alarmin S100B is regulated by poly(ADP-ribose) polymerase-1. Glia. vol 64. issue 11. 2018-01-04. PMID:27444121. |
brain injury resulting from stroke or trauma can be exacerbated by the release of proinflammatory cytokines, proteases, and reactive oxygen species by activated microglia. |
2018-01-04 |
2023-08-13 |
Not clear |