| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mayur S Parmar, Juliann D Jaumotte, Stephanie L Wyrostek, Michael J Zigmond, Jane E Cavanaug. Role of ERK1, 2, and 5 in dopamine neuron survival during aging. Neurobiology of aging. vol 35. issue 3. 2014-09-29. PMID:24411019. |
in this study, we examined erk1, 2, and 5 expression and activation in the substantia nigra (sn), striatum (str), and ventral tegmental area (vta) during aging. |
2014-09-29 |
2023-08-12 |
Not clear |
| Yuan-Yi Ma, Shu-Zhen Kong, Li-Jiang Yang, Jin-Lan Meng, Le-Chun Lv, Min H. [Sexual dimorphisms of dopaminergic neurons in rat substantia nigra]. Sheng li xue bao : [Acta physiologica Sinica]. vol 59. issue 6. 2014-09-26. PMID:18157467. |
parkinson's disease (pd), caused by the mesencephalic substantia nigra (sn) dopaminergic neuronal loss, displays sexual difference, i.e., the incidence is higher and the symptoms are more intense in males than that in females. |
2014-09-26 |
2023-08-12 |
rat |
| Ryo Shimada, Keiichi Abe, Rui Furutani, Kazuhiko Kibayash. Changes in dopamine transporter expression in the midbrain following traumatic brain injury: an immunohistochemical and in situ hybridization study in a mouse model. Neurological research. vol 36. issue 3. 2014-09-25. PMID:24512017. |
magnetic resonance imaging has revealed that traumatic brain injury (tbi) can cause primary lesions in the midbrain including the substantia nigra (sn). |
2014-09-25 |
2023-08-12 |
mouse |
| Ashwin G Ramayya, Kareem A Zaghloul, Christoph T Weidemann, Gordon H Baltuch, Michael J Kahan. Electrophysiological evidence for functionally distinct neuronal populations in the human substantia nigra. Frontiers in human neuroscience. vol 8. 2014-09-24. PMID:25249957. |
the human substantia nigra (sn) is thought to consist of two functionally distinct neuronal populations-dopaminergic (da) neurons in the pars compacta subregion and gaba-ergic neurons in the pars reticulata subregion. |
2014-09-24 |
2023-08-13 |
human |
| Elena Dragicevic, Christina Poetschke, Johanna Duda, Falk Schlaudraff, Stephan Lammel, Julia Schiemann, Michael Fauler, Andrea Hetzel, Masahiko Watanabe, Rafael Lujan, Robert C Malenka, Joerg Striessnig, Birgit Lis. Cav1.3 channels control D2-autoreceptor responses via NCS-1 in substantia nigra dopamine neurons. Brain : a journal of neurology. vol 137. issue Pt 8. 2014-09-23. PMID:24934288. |
furthermore, we detected elevated substantia nigra dopamine messenger rna levels of ncs-1 (but not cav1.2 or cav1.3) after cocaine in mice, as well as in remaining human sn da neurons in parkinson's disease. |
2014-09-23 |
2023-08-13 |
mouse |
| Yuanyuan Qin, Wenzhen Zhu, Chuanjia Zhan, Lingyun Zhao, Jianzhi Wang, Qing Tian, Wei Wan. Investigation on positive correlation of increased brain iron deposition with cognitive impairment in Alzheimer disease by using quantitative MR R2' mapping. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 31. issue 4. 2014-09-09. PMID:21823025. |
we statistically analyzed the r2' and iron concentrations of bilateral hippocampus (hp), parietal cortex (pc), frontal white matter (fwm), putamen (pu), caudate nucleus (cn), thalamus (th), red nucleus (rn), substantia nigra (sn), and dentate nucleus (dn) of the cerebellum for the correlation with the severity of dementia. |
2014-09-09 |
2023-08-12 |
human |
| Mario Riverol, Cristina Ordóñez, María Collantes, Carla DiCaudo, Iván Peñuelas, Javier Arbizu, Irene Marcilla, María R Luqui. Levodopa induces long-lasting modification in the functional activity of the nigrostriatal pathway. Neurobiology of disease. vol 62. 2014-09-03. PMID:24076099. |
the levels of several striatal dopaminergic markers and the number of surviving dopaminergic neurons in the substantia nigra (sn) were also assessed. |
2014-09-03 |
2023-08-12 |
monkey |
| Akiyo Natsubori, Ken-ichi Honma, Sato Honm. Dual regulation of clock gene Per2 expression in discrete brain areas by the circadian pacemaker and methamphetamine-induced oscillator in rats. The European journal of neuroscience. vol 39. issue 2. 2014-09-03. PMID:24438490. |
circadian per2 rhythms in r-map rats were not affected in the scn but were slightly phase-advanced in the olfactory bulb (ob), caudate-putamen (cpu) and substantia nigra (sn) as compared with r-water rats. |
2014-09-03 |
2023-08-12 |
rat |
| J A Teske, C J Billington, C M Kot. Mechanisms underlying obesity resistance associated with high spontaneous physical activity. Neuroscience. vol 256. 2014-08-27. PMID:24161277. |
we further tested whether orexin action on dopamine one receptors (da1r) in the substantia nigra (sn) plays an important role in the generation of spa. |
2014-08-27 |
2023-08-12 |
rat |
| Jun Ming Wan. Allopregnanolone and neurogenesis in the nigrostriatal tract. Frontiers in cellular neuroscience. vol 8. 2014-08-27. PMID:25161608. |
loss of dopamine neurons in the substantia nigra (sn) is one of the main pathological features of parkinson's and also in, at least, a subset of alzheimer's patients. |
2014-08-27 |
2023-08-13 |
mouse |
| Z Zhang, L Hou, J-L Song, N Song, Y-J Sun, X Lin, X-L Wang, F-Z Zhang, Y-L G. Pro-inflammatory cytokine-mediated ferroportin down-regulation contributes to the nigral iron accumulation in lipopolysaccharide-induced Parkinsonian models. Neuroscience. vol 257. 2014-08-26. PMID:24183966. |
pro-inflammatory cytokines induced by inflammation and iron accumulation in the substantia nigra (sn) have been implicated in the pathogenesis of parkinson's disease (pd). |
2014-08-26 |
2023-08-12 |
rat |
| Timothy M Ellmore, Richard J Castriotta, Katie L Hendley, Brian M Aalbers, Erin Furr-Stimming, Ashley J Hood, Jessika Suescun, Michelle R Beurlot, Roy T Hendley, Mya C Schies. Altered nigrostriatal and nigrocortical functional connectivity in rapid eye movement sleep behavior disorder. Sleep. vol 36. issue 12. 2014-08-25. PMID:24293763. |
in the current study, we tested the hypothesis of altered functional connections of the substantia nigra (sn) in patients in whom rbd was diagnosed. |
2014-08-25 |
2023-08-12 |
Not clear |
| Eun Hee Ahn, Dae Won Kim, Min Jea Shin, Young Nam Kim, Hye Ri Kim, Su Jung Woo, So Mi Kim, Duk-Soo Kim, Joon Kim, Jinseu Park, Won Sik Eum, Hyun Sook Hwang, Soo Young Cho. PEP-1-ribosomal protein S3 protects dopaminergic neurons in an MPTP-induced Parkinson's disease mouse model. Free radical biology & medicine. vol 55. 2014-08-20. PMID:23178948. |
parkinson's disease (pd) is a neurodegenerative disease characterized by a gradual loss of dopaminergic (da) neurons in the substantia nigra (sn) of the brain. |
2014-08-20 |
2023-08-12 |
mouse |
| Wenjiao Tai, Xuan Ye, Xiuqi Bao, Baozhong Zhao, Xiaoliang Wang, Dan Zhan. Inhibition of Src tyrosine kinase activity by squamosamide derivative FLZ attenuates neuroinflammation in both in vivo and in vitro Parkinson's disease models. Neuropharmacology. vol 75. 2014-08-19. PMID:23916477. |
flz treatment significantly improved the motor dysfunction of pd model rats induced by intra-nigral injection of lps and this beneficial effect of flz attributed to the inhibition of microglial over-activation and the protection on dopaminergic neurons in the substantia nigra (sn). |
2014-08-19 |
2023-08-12 |
rat |
| Michaeline L Hebron, Irina Lonskaya, Charbel E-H Mouss. Tyrosine kinase inhibition facilitates autophagic SNCA/α-synuclein clearance. Autophagy. vol 9. issue 8. 2014-08-13. PMID:23787811. |
parkinson disease (pd) is a movement disorder characterized by death of dopaminergic substantia nigra (sn) neurons and brain accumulation of snca. |
2014-08-13 |
2023-08-12 |
mouse |
| Kimberlee D'Ardenne, Terry Lohrenz, Krystle A Bartley, P Read Montagu. Computational heterogeneity in the human mesencephalic dopamine system. Cognitive, affective & behavioral neuroscience. vol 13. issue 4. 2014-08-11. PMID:23943512. |
blood oxygenation level dependent responses in regions of substantia nigra (sn) and ventral tegmental area (vta), where dopamine neurons are located, coded for td and fictive errors, and additionally were related to the motivational salience signal. |
2014-08-11 |
2023-08-12 |
human |
| Christopher A Bates, Wei Zhen. Brain disposition of α-Synuclein: roles of brain barrier systems and implications for Parkinson's disease. Fluids and barriers of the CNS. vol 11. 2014-08-05. PMID:25093076. |
parkinson's disease (pd) is a neurodegenerative disorder characterized by the accumulation of α-synuclein (a-syn) into lewy body inclusions and the loss of dopaminergic neurons in the substantia nigra (sn). |
2014-08-05 |
2023-08-13 |
Not clear |
| Eung Seok Oh, Chaejeong Heo, Ji Seon Kim, Minah Suh, Young Hee Lee, Jong-Min Ki. Hyperspectral fluorescence imaging for cellular iron mapping in the in vitro model of Parkinson's disease. Journal of biomedical optics. vol 19. issue 5. 2014-08-04. PMID:24297062. |
parkinson's disease (pd) is characterized by progressive dopaminergic cell loss in the substantia nigra (sn) and elevated iron levels demonstrated by autopsy. |
2014-08-04 |
2023-08-12 |
Not clear |
| Anna Czarnecka, Tomasz Lenda, Helena Domin, Jolanta Konieczny, Maria Smiałowska, Elżbieta Lorenc-Koc. Alterations in the expression of nNOS in the substantia nigra and subthalamic nucleus of 6-OHDA-lesioned rats: the effects of chronic treatment with l-DOPA and the nitric oxide donor, molsidomine. Brain research. vol 1541. 2014-07-28. PMID:24129225. |
degeneration of dopaminergic neurons in the substantia nigra (sn) in parkinson's disease leads to disturbances in the nitrergic transmission in the basal ganglia. |
2014-07-28 |
2023-08-12 |
rat |
| Miklos Antal, Brandon M Beneduce, Wade G Regeh. The substantia nigra conveys target-dependent excitatory and inhibitory outputs from the basal ganglia to the thalamus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 23. 2014-07-25. PMID:24899724. |
the substantia nigra (sn) consists of gabaergic neurons of the pars reticulata that inhibit thalamic neurons and provide the primary output of the bg, and dopaminergic neurons of the pars compacta that modulate thalamic excitability. |
2014-07-25 |
2023-08-13 |
mouse |