| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Miguel Á Luján, Dan P Covey, Reana Young-Morrison, LanYuan Zhang, Andrew Kim, Fiorella Morgado, Sachin Patel, Caroline E Bass, Carlos Paladini, Joseph F Chee. Mobilization of endocannabinoids by midbrain dopamine neurons is required for the encoding of reward prediction. Nature communications. vol 14. issue 1. 2023-11-24. PMID:37985770. |
however, it is not clear whether mobilization of 2-ag specifically from midbrain dopamine neurons is necessary for dopaminergic responses to external stimuli predicting forthcoming reward. |
2023-11-24 |
2023-11-28 |
mouse |
| Abid Ali, Kiryl Zhaliazka, Tianyi Dou, Aidan P Holman, Dmitry Kurousk. The toxicities of A30P and A53T α-synuclein fibrils can be uniquely altered by the length and saturation of fatty acids in phosphatidylserine. The Journal of biological chemistry. vol 299. issue 12. 2023-11-21. PMID:37890776. |
progressive degeneration of dopaminergic neurons in the midbrain, hypothalamus, and thalamus is a hallmark of parkinson's disease (pd). |
2023-11-21 |
2023-11-29 |
Not clear |
| Sandra Blaess, Sabine Krabb. Cell type specificity for circuit output in the midbrain dopaminergic system. Current opinion in neurobiology. vol 83. 2023-11-16. PMID:37972537. |
cell type specificity for circuit output in the midbrain dopaminergic system. |
2023-11-16 |
2023-11-20 |
Not clear |
| Sandra Blaess, Sabine Krabb. Cell type specificity for circuit output in the midbrain dopaminergic system. Current opinion in neurobiology. vol 83. 2023-11-16. PMID:37972537. |
midbrain dopaminergic neurons are a relatively small group of neurons in the mammalian brain controlling a wide range of behaviors. |
2023-11-16 |
2023-11-20 |
Not clear |
| Valentin Plateau, Jérôme Baufreton, Morgane Le Bon-Jég. Age-Dependent Modulation of Layer V Pyramidal Neuron Excitability in the Mouse Primary Motor Cortex by D1 Receptor Agonists and Antagonists. Neuroscience. 2023-11-12. PMID:37952579. |
the primary motor cortex (m1) receives dopaminergic (daergic) projections from the midbrain which play a key role in modulating motor and cognitive processes, such as motor skill learning. |
2023-11-12 |
2023-11-20 |
mouse |
| Jeffrey Kim, Etienne W Daadi, Elyas Sebastien Daadi, Thomas Oh, Michela Deleidi, Marcel M Daad. Cells. vol 12. issue 21. 2023-11-10. PMID:37947628. |
parkinson's disease (pd) is the second most prevalent neurodegenerative disease, characterized by the loss of midbrain dopaminergic neurons which leads to impaired motor and cognitive functions. |
2023-11-10 |
2023-11-20 |
Not clear |
| Olivier Lurette, Rebeca Martín-Jiménez, Mehtab Khan, Razan Sheta, Stéphanie Jean, Mia Schofield, Maxime Teixeira, Raquel Rodriguez-Aller, Isabelle Perron, Abid Oueslati, Etienne Hebert-Chatelai. Aggregation of alpha-synuclein disrupts mitochondrial metabolism and induce mitophagy via cardiolipin externalization. Cell death & disease. vol 14. issue 11. 2023-11-10. PMID:37949858. |
aggregation of α-synuclein also leads to lower mitochondrial content in human dopaminergic neurons and in mouse midbrain. |
2023-11-10 |
2023-11-20 |
mouse |
| Nicole Burkert, Shoumik Roy, Max Häusler, Dominik Wuttke, Sonja Müller, Johanna Wiemer, Helene Hollmann, Marvin Oldrati, Jorge Ramirez-Franco, Julia Benkert, Michael Fauler, Johanna Duda, Jean-Marc Goaillard, Christina Pötschke, Moritz Münchmeyer, Rosanna Parlato, Birgit Lis. Deep learning-based image analysis identifies a DAT-negative subpopulation of dopaminergic neurons in the lateral Substantia nigra. Communications biology. vol 6. issue 1. 2023-11-10. PMID:37950046. |
we utilised dlap to analyse subtypes of tyrosine hydroxylase (th)-positive dopaminergic midbrain neurons in mouse and human brain-sections. |
2023-11-10 |
2023-11-20 |
mouse |
| Zhaoyang Liu, Jessica Lemus, Irina V Smirnova, Wen Li. Rehabilitation for non-motor symptoms for patients with Parkinson's disease from an α-synuclein perspective: a narrative review. Exploration of neuroprotective therapy. vol 3. issue 4. 2023-11-03. PMID:37920444. |
pd is characterized by neuronal lewy bodies present in the substantia nigra of the midbrain and the loss of dopaminergic neurons with various motor and non-motor symptoms associated with the disease. |
2023-11-03 |
2023-11-08 |
Not clear |
| Hye Yun Kim, Jieun Lee, Hyun-Jin Kim, Byeong Eun Lee, Jaewook Jeong, Eun Jeong Cho, Hyun-Jun Jang, Kyeong Jin Shin, Min Ji Kim, Young Chan Chae, Seung Eun Lee, Kyungjae Myung, Ja-Hyun Baik, Pann-Ghill Suh, Jae-Ick Ki. PLCγ1 in dopamine neurons critically regulates striatal dopamine release via VMAT2 and synapsin III. Experimental & molecular medicine. 2023-11-01. PMID:37907739. |
we found that cell type-specific deletion of plcγ1 does not adversely affect the development and cellular morphology of midbrain dopamine neurons but does facilitate dopamine release from dopaminergic axon terminals in the striatum. |
2023-11-01 |
2023-11-08 |
mouse |
| Yasemin Açar, Duygu Ağagündüz, Paola De Cicco, Raffaele Capass. Flavonoids: Their putative neurologic roles, epigenetic changes, and gut microbiota alterations in Parkinson's disease. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 168. 2023-11-01. PMID:37913731. |
parkinson's disease (pd), a neurodegenerative disorder, is characterized by the degeneration of progressive dopaminergic (da) neurons in the substantia nigra region of the human midbrain. |
2023-11-01 |
2023-11-08 |
human |
| Nataliia V Katolikova, Anastasia N Vaganova, Daria D Shafranskaya, Evgeniya V Efimova, Anna B Malashicheva, Raul R Gainetdino. Expression Pattern of Trace Amine-Associated Receptors during Differentiation of Human Pluripotent Stem Cells to Dopaminergic Neurons. International journal of molecular sciences. vol 24. issue 20. 2023-10-30. PMID:37894992. |
the expression of several taar types (particularly taar5) was also found in human dopaminergic neuron-enriched zones in the midbrain. |
2023-10-30 |
2023-11-08 |
human |
| Anya Stetsenko, Tibor Koo. Neuronal implementation of the temporal difference learning algorithm in the midbrain dopaminergic system. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 45. 2023-10-30. PMID:37903252. |
neuronal implementation of the temporal difference learning algorithm in the midbrain dopaminergic system. |
2023-10-30 |
2023-11-08 |
Not clear |
| Heechang Moon, Bokwang Kim, Inbeom Kwon, Yohan O. Challenges involved in cell therapy for Parkinson's disease using human pluripotent stem cells. Frontiers in cell and developmental biology. vol 11. 2023-10-27. PMID:37886394. |
various research groups are focused on differentiating hpscs into ventral midbrain dopaminergic (vmda) progenitors, which have the potential to further differentiate into neurons closely resembling da neurons found in the substantia nigra pars compacta (snpc) after transplantation, providing a promising treatment option for pd. |
2023-10-27 |
2023-11-08 |
human |
| Yu-Kai Wang, Lin Feng, Ai-Jin Ma, Jie Hao, Ying Zhang, Yue-Jun Chen, Zhi-Guo Chen, Jun-Ying Yu, Yan Liu, Chang-Mei Liu, Yu Zhang, Chang-Lin Wang, Zhao-Qian Teng, Jia-Xi Zhou, Tian-Qing Li, Liu Wang, Bo-Qiang Fu, Yu Vincent Fu, Li-Jun Zhu, Ling-Min Liang, Jia-Ni Cao, Lei Wang, Qi Zhou, Andy Peng Xiang, Bao-Yang Hu, Tong-Biao Zha. Human midbrain dopaminergic progenitors. Cell proliferation. 2023-10-26. PMID:37881164. |
human midbrain dopaminergic progenitors. |
2023-10-26 |
2023-11-08 |
human |
| Yu-Kai Wang, Lin Feng, Ai-Jin Ma, Jie Hao, Ying Zhang, Yue-Jun Chen, Zhi-Guo Chen, Jun-Ying Yu, Yan Liu, Chang-Mei Liu, Yu Zhang, Chang-Lin Wang, Zhao-Qian Teng, Jia-Xi Zhou, Tian-Qing Li, Liu Wang, Bo-Qiang Fu, Yu Vincent Fu, Li-Jun Zhu, Ling-Min Liang, Jia-Ni Cao, Lei Wang, Qi Zhou, Andy Peng Xiang, Bao-Yang Hu, Tong-Biao Zha. Human midbrain dopaminergic progenitors. Cell proliferation. 2023-10-26. PMID:37881164. |
human midbrain dopaminergic progenitors (mdaps) are one of the most representative cell types in both basic research and clinical applications. |
2023-10-26 |
2023-11-08 |
human |
| Yu-Kai Wang, Lin Feng, Ai-Jin Ma, Jie Hao, Ying Zhang, Yue-Jun Chen, Zhi-Guo Chen, Jun-Ying Yu, Yan Liu, Chang-Mei Liu, Yu Zhang, Chang-Lin Wang, Zhao-Qian Teng, Jia-Xi Zhou, Tian-Qing Li, Liu Wang, Bo-Qiang Fu, Yu Vincent Fu, Li-Jun Zhu, Ling-Min Liang, Jia-Ni Cao, Lei Wang, Qi Zhou, Andy Peng Xiang, Bao-Yang Hu, Tong-Biao Zha. Human midbrain dopaminergic progenitors. Cell proliferation. 2023-10-26. PMID:37881164. |
"human midbrain dopaminergic progenitor" jointly drafted and agreed upon by experts from the chinese society for stem cell research, is the first guideline for human mdaps in china. |
2023-10-26 |
2023-11-08 |
human |
| Pol Bech, Sylvain Crochet, Robin Dard, Parviz Ghaderi, Yanqi Liu, Meriam Malekzadeh, Carl C H Petersen, Mauro Pulin, Anthony Renard, Christos Sourmpi. Striatal Dopamine Signals and Reward Learning. Function (Oxford, England). vol 4. issue 6. 2023-10-16. PMID:37841525. |
here, we review evidence suggesting that midbrain dopaminergic neurons signal reward prediction error, driving synaptic plasticity in the striatum underlying learning. |
2023-10-16 |
2023-11-08 |
Not clear |
| Yalan Chen, Junxin Kuang, Yimei Niu, Hongyao Zhu, Xiaoxia Chen, Kwok-Fai So, Anding Xu, Lingling Sh. Multiple factors to assist human-derived induced pluripotent stem cells to efficiently differentiate into midbrain dopaminergic neurons. Neural regeneration research. vol 19. issue 4. 2023-10-16. PMID:37843228. |
multiple factors to assist human-derived induced pluripotent stem cells to efficiently differentiate into midbrain dopaminergic neurons. |
2023-10-16 |
2023-11-08 |
human |
| Yalan Chen, Junxin Kuang, Yimei Niu, Hongyao Zhu, Xiaoxia Chen, Kwok-Fai So, Anding Xu, Lingling Sh. Multiple factors to assist human-derived induced pluripotent stem cells to efficiently differentiate into midbrain dopaminergic neurons. Neural regeneration research. vol 19. issue 4. 2023-10-16. PMID:37843228. |
midbrain dopaminergic neurons play an important role in the etiology of neurodevelopmental and neurodegenerative diseases. |
2023-10-16 |
2023-11-08 |
human |